Alignment of alleles: Human IGKV4-1

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).



                                    1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                   D   I   V   M   T   Q   S   P   D   S   L   A   V   S   L   G   E   R   A   T
  Z00023  ,IGKV4-1*01,B3          GAC ATC GTG ATG ACC CAG TCT CCA GAC TCC CTG GCT GTG TCT CTG GGC GAG AGG GCC ACC

  X93640  ,IGKV4-1*01,DPK24       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  S56916  ,IGKV4-1*01,VkIV-GL     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  Z46615  ,IGKV4-1*01,FSA10gl     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  L33853  ,IGKV4-1*01             --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  AF017732,IGKV4-1*01             --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                          ____________________CDR1-IMGT__________________
                                   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                   I   N   C   K   S   S   Q   S   V   L   Y   S   S   N   N   K   N   Y   L   A
  Z00023  ,IGKV4-1*01,B3          ATC AAC TGC AAG TCC AGC CAG AGT GTT TTA TAC AGC TCC AAC AAT AAG AAC TAC TTA GCT

  X93640  ,IGKV4-1*01,DPK24       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  S56916  ,IGKV4-1*01,VkIV-GL     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  Z46615  ,IGKV4-1*01,FSA10gl     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  L33853  ,IGKV4-1*01             --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  AF017732,IGKV4-1*01             --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                                                              ______________CDR2-
                                   41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                   W   Y   Q   Q   K   P   G   Q   P   P   K   L   L   I   Y   W   A   S
  Z00023  ,IGKV4-1*01,B3          TGG TAC CAG CAG AAA CCA GGA CAG CCT CCT AAG CTG CTC ATT TAC TGG GCA TCT ... ...

  X93640  ,IGKV4-1*01,DPK24       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

  S56916  ,IGKV4-1*01,VkIV-GL     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

  Z46615  ,IGKV4-1*01,FSA10gl     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

  L33853  ,IGKV4-1*01             --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

  AF017732,IGKV4-1*01             --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

                                  IMGT_______________
                                   61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                                       T   R   E   S   G   V   P       D   R   F   S   G   S   G
  Z00023  ,IGKV4-1*01,B3          ... ... ... ... ... ACC CGG GAA TCC GGG GTC CCT ... GAC CGA TTC AGT GGC AGC GGG

  X93640  ,IGKV4-1*01,DPK24       ... ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---

  S56916  ,IGKV4-1*01,VkIV-GL     ... ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---

  Z46615  ,IGKV4-1*01,FSA10gl     ... ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---

  L33853  ,IGKV4-1*01             ... ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---

  AF017732,IGKV4-1*01             ... ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---


                                   81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                           S   G   T   D   F   T   L   T   I   S   S   L   Q   A   E   D   V   A
  Z00023  ,IGKV4-1*01,B3          ... ... TCT GGG ACA GAT TTC ACT CTC ACC ATC AGC AGC CTG CAG GCT GAA GAT GTG GCA

  X93640  ,IGKV4-1*01,DPK24       ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  S56916  ,IGKV4-1*01,VkIV-GL     ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  Z46615  ,IGKV4-1*01,FSA10gl     ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  L33853  ,IGKV4-1*01             ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  AF017732,IGKV4-1*01             ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                  _________CDR3-IMGT____________
                                  101 102 103 104 105 106 107 108 109 110 111
                                   V   Y   Y   C   Q   Q   Y   Y   S   T   P
  Z00023  ,IGKV4-1*01,B3          GTT TAT TAC TGT CAG CAA TAT TAT AGT ACT CCT CC

  X93640  ,IGKV4-1*01,DPK24       --- --- --- --- --- --- --- --- --- --- --- --

  S56916  ,IGKV4-1*01,VkIV-GL     --- --- --- --- --- --- --- --- --- --- --- --

  Z46615  ,IGKV4-1*01,FSA10gl     --- --- --- --- --- --- --- --- --- --- ---

  L33853  ,IGKV4-1*01             --- --- --- --- --- --- --- --- --- --- ---

  AF017732,IGKV4-1*01             --- --- --- --- --- --- --- --- --- --- --- --


Created: 25/03/1997
Last updated: Monday, 11-Jul-2011 12:56:55 CEST
Author: Valérie Barbié
Contact: Marie-Paule Lefranc

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.


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