Alignment of alleles: Human IGKV3-20

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).



                                    1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                   E   I   V   L   T   Q   S   P   G   T   L   S   L   S   P   G   E   R   A   T
  X12686  ,IGKV3-20*01,A27        GAA ATT GTG TTG ACG CAG TCT CCA GGC ACC CTG TCT TTG TCT CCA GGG GAA AGA GCC ACC

  M15038  ,IGKV3-20*01,A27a       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  M15039  ,IGKV3-20*01,humkv321

  X93639  ,IGKV3-20*01,DPK22      --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
                                                                       P   C   L   C   L
  X56593  ,IGKV3-20*01,Tou-kv325  --- --- --- --- --- --- --- --- --- C-- TGT CT- -GT CTC --- --- --- --- --- ---
                                                                   A
  L37729  ,IGKV3-20*02,13K18      --- --- --- --- --A --- --- --- -C- --- --- --- --- --- --- --- --- --- --- ---

                                                          ____________________CDR1-IMGT__________________
                                   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                   L   S   C   R   A   S   Q   S   V   S   S   S   Y                       L   A
  X12686  ,IGKV3-20*01,A27        CTC TCC TGC AGG GCC AGT CAG AGT GTT AGC AGC AGC TAC ... ... ... ... ... TTA GCC

  M15038  ,IGKV3-20*01,A27a       --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- ---

  M15039  ,IGKV3-20*01,humkv321

  X93639  ,IGKV3-20*01,DPK22      --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- ---

  X56593  ,IGKV3-20*01,Tou-kv325  --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- ---

  L37729  ,IGKV3-20*02,13K18      --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... --- ---

                                                                                              ______________CDR2-
                                   41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                   W   Y   Q   Q   K   P   G   Q   A   P   R   L   L   I   Y   G   A   S
  X12686  ,IGKV3-20*01,A27        TGG TAC CAG CAG AAA CCT GGC CAG GCT CCC AGG CTC CTC ATC TAT GGT GCA TCC ... ...

  M15038  ,IGKV3-20*01,A27a       --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

  M15039  ,IGKV3-20*01,humkv321                             - --- --- --- --- --- --- --- --- --- --- --- ... ...

  X93639  ,IGKV3-20*01,DPK22      --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

  X56593  ,IGKV3-20*01,Tou-kv325  --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

  L37729  ,IGKV3-20*02,13K18      --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

                                  IMGT_______________
                                   61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                                       S   R   A   T   G   I   P       D   R   F   S   G   S   G
  X12686  ,IGKV3-20*01,A27        ... ... ... ... ... AGC AGG GCC ACT GGC ATC CCA ... GAC AGG TTC AGT GGC AGT GGG

  M15038  ,IGKV3-20*01,A27a       ... ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---

  M15039  ,IGKV3-20*01,humkv321   ... ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---

  X93639  ,IGKV3-20*01,DPK22      ... ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---

  X56593  ,IGKV3-20*01,Tou-kv325  ... ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---
                                                                                       A
  L37729  ,IGKV3-20*02,13K18      ... ... ... ... ... --- --- --- --- --- --- --- ... -CA --- --- --- --- --- ---


                                   81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                           S   G   T   D   F   T   L   T   I   S   R   L   E   P   E   D   F   A
  X12686  ,IGKV3-20*01,A27        ... ... TCT GGG ACA GAC TTC ACT CTC ACC ATC AGC AGA CTG GAG CCT GAA GAT TTT GCA

  M15038  ,IGKV3-20*01,A27a       ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  M15039  ,IGKV3-20*01,humkv321   ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  X93639  ,IGKV3-20*01,DPK22      ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  X56593  ,IGKV3-20*01,Tou-kv325  ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

  L37729  ,IGKV3-20*02,13K18      ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                  _________CDR3-IMGT____________
                                  101 102 103 104 105 106 107 108 109 110 111
                                   V   Y   Y   C   Q   Q   Y   G   S   S   P
  X12686  ,IGKV3-20*01,A27        GTG TAT TAC TGT CAG CAG TAT GGT AGC TCA CCT CC

  M15038  ,IGKV3-20*01,A27a       --- --- --- --- --- --- --- --- --- --- --- --

  M15039  ,IGKV3-20*01,humkv321   --- --- --- --- --- --- --- --- --- --- --- --

  X93639  ,IGKV3-20*01,DPK22      --- --- --- --- --- --- --- --- --- --- --- --

  X56593  ,IGKV3-20*01,Tou-kv325  --- --- --- --- --- --- --- --- --- --- --

  L37729  ,IGKV3-20*02,13K18      --T --- --- --- --- -

IMGT note:
Deletion of 1 nucleotide (a) between nucleotides 27 and 28, and insertion of 1 nucleotide (c) between nucleotides 42 and 43 in X56593 in EMBL flat file are probably sequencing errors.


Created: 25/03/1997
Last updated: Monday, 11-Jul-2011 12:56:56 CEST
Author: Valérie Barbié
Contact: Marie-Paule Lefranc

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