IMGT Web resources: IMGT repertoire

Alignment of alleles: Human IGKV2D-30

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).


                                    1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                   D   V   V   M   T   Q   S   P   L   S   L   P   V   T   L   G   Q   P   A   S
  X63402  ,IGKV2D-30*01,A1        GAT GTT GTG ATG ACT CAG TCT CCA CTC TCC CTG CCC GTC ACC CTT GGA CAG CCG GCC TCC

  X93636  ,IGKV2D-30*01,DPK19     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                          ____________________CDR1-IMGT__________________
                                   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                   I   S   C   R   S   S   Q   S   L   V   Y   S   D   G   N   T   Y       L   N
  X63402  ,IGKV2D-30*01,A1        ATC TCC TGC AGG TCT AGT CAA AGC CTC GTA TAC AGT GAT GGA AAC ACC TAC ... TTG AAT

  X93636  ,IGKV2D-30*01,DPK19     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... --- ---

                                                                                              ______________CDR2-
                                   41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                   W   F   Q   Q   R   P   G   Q   S   P   R   R   L   I   Y   K   V   S
  X63402  ,IGKV2D-30*01,A1        TGG TTT CAG CAG AGG CCA GGC CAA TCT CCA AGG CGC CTA ATT TAT AAG GTT TCT ... ...

  X93636  ,IGKV2D-30*01,DPK19     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

                                  IMGT_______________
                                   61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                                       N   W   D   S   G   V   P       D   R   F   S   G   S   G
  X63402  ,IGKV2D-30*01,A1        ... ... ... ... ... AAC TGG GAC TCT GGG GTC CCA ... GAC AGA TTC AGC GGC AGT GGG

  X93636  ,IGKV2D-30*01,DPK19     ... ... ... ... ... --- --- --- --- --- --- --- ... --- --- --- --- --- --- ---


                                   81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                           S   G   T   D   F   T   L   K   I   S   R   V   E   A   E   D   V   G
  X63402  ,IGKV2D-30*01,A1        ... ... TCA GGC ACT GAT TTC ACA CTG AAA ATC AGC AGG GTG GAG GCT GAG GAT GTT GGG

  X93636  ,IGKV2D-30*01,DPK19     ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                  _________CDR3-IMGT____________
                                  101 102 103 104 105 106 107 108 109 110 111
                                   V   Y   Y   C   M   Q   G   T   H   W   P
  X63402  ,IGKV2D-30*01,A1        GTT TAT TAC TGC ATG CAA GGT ACA CAC TGG CCT CC

  X93636  ,IGKV2D-30*01,DPK19     --- --- --- --- --- --- --- --- --- --- --- --

IMGT note:
Only one allele (*01) is currently known for IGKV2-30 and IGKV2D-30 that differs by a single nucleotide leading to an amino acid change.
c199>t; R67>W
It cannot be ruled out that a not yet identified allele of IGKV2-30 has the same sequence as IGKV2D-30*01.

Created: 25/03/1997
Last updated: Monday, 11-Jul-2011 12:56:56 CEST
Author: Valérie Barbié
Contact: Marie-Paule Lefranc

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