IMGT Web resources: IMGT repertoire

Alignment of alleles: Human IGKV1-8

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).



                                    1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                   A   I   R   M   T   Q   S   P   S   S   F   S   A   S   T   G   D   R   V   T
  Z00014  ,IGKV1-8*01,L9          GCC ATC CGG ATG ACC CAG TCT CCA TCC TCA TTC TCT GCA TCT ACA GGA GAC AGA GTC ACC

                                                          ____________________CDR1-IMGT__________________
                                   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                   I   T   C   R   A   S   Q   G   I   S   S   Y                           L   A
  Z00014  ,IGKV1-8*01,L9          ATC ACT TGT CGG GCG AGT CAG GGT ATT AGC AGT TAT ... ... ... ... ... ... TTA GCC

                                                                                              ______________CDR2-
                                   41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                   W   Y   Q   Q   K   P   G   K   A   P   K   L   L   I   Y   A   A   S
  Z00014  ,IGKV1-8*01,L9          TGG TAT CAG CAA AAA CCA GGG AAA GCC CCT AAG CTC CTG ATC TAT GCT GCA TCC ... ...

                                  IMGT_______________
                                   61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                                       T   L   Q   S   G   V   P       S   R   F   S   G   S   G
  Z00014  ,IGKV1-8*01,L9          ... ... ... ... ... ACT TTG CAA AGT GGG GTC CCA ... TCA AGG TTC AGC GGC AGT GGA


                                   81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                           S   G   T   D   F   T   L   T   I   S   C   L   Q   S   E   D   F   A
  Z00014  ,IGKV1-8*01,L9          ... ... TCT GGG ACA GAT TTC ACT CTC ACC ATC AGC TGC CTG CAG TCT GAA GAT TTT GCA

                                                  _________CDR3-IMGT____________
                                  101 102 103 104 105 106 107 108 109 110 111
                                   T   Y   Y   C   Q   Q   Y   Y   S   Y   P
  Z00014  ,IGKV1-8*01,L9          ACT TAT TAC TGT CAA CAG TAT TAT AGT TAC CCT CC

Created: 25/03/1997
Last updated: Monday, 11-Jul-2011 12:56:56 CEST
Author: Valérie Barbié
Contact: Marie-Paule Lefranc

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.

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