Alignment of alleles: Human IGKV1-16

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).



                                    1   2   3   4   5   6   7   8   9  10  11  12  13  14  15  16  17  18  19  20
                                   D   I   Q   M   T   Q   S   P   S   S   L   S   A   S   V   G   D   R   V   T
  J00248  ,IGKV1-16*01,L1         GAC ATC CAG ATG ACC CAG TCT CCA TCC TCA CTG TCT GCA TCT GTA GGA GAC AGA GTC ACC
  
  FM164406,IGKV1-16*02            --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                           ____________________CDR1-IMGT__________________
                                   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
                                   I   T   C   R   A   S   Q   G   I   S   N   Y                           L   A
  J00248  ,IGKV1-16*01,L1         ATC ACT TGT CGG GCG AGT CAG GGC ATT AGC AAT TAT ... ... ... ... ... ... TTA GCC
  
  FM164406,IGKV1-16*02            --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- ---

                                                                                              ______________CDR2-
                                   41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60
                                   W   F   Q   Q   K   P   G   K   A   P   K   S   L   I   Y   A   A   S
  J00248  ,IGKV1-16*01,L1         TGG TTT CAG CAG AAA CCA GGG AAA GCC CCT AAG TCC CTG ATC TAT GCT GCA TCC ... ...

  FM164406,IGKV1-16*02            --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ...

                                   IMGT_______________
                                   61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80
                                                       S   L   Q   S   G   V   P       S   R   F   S   G   S   G
  J00248  ,IGKV1-16*01,L1         ... ... ... ... ... AGT TTG CAA AGT GGG GTC CCA ... TCA AGG TTC AGC GGC AGT GGA
                                                                                           K
  FM164406,IGKV1-16*02            ... ... ... ... ... --- --- --- --- --- --- --- ... --- -A- --- --- --- --- ---


                                   81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100
                                           S   G   T   D   F   T   L   T   I   S   S   L   Q   P   E   D   F   A
  J00248  ,IGKV1-16*01,L1         ... ... TCT GGG ACA GAT TTC ACT CTC ACC ATC AGC AGC CTG CAG CCT GAA GAT TTT GCA

  FM164406,IGKV1-16*02            ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

                                                  _________CDR3-IMGT____________
                                  101 102 103 104 105 106 107 108 109 110 111
                                   T   Y   Y   C   Q   Q   Y   N   S   Y   P
  J00248  ,IGKV1-16*01,L1         ACT TAT TAC TGC CAA CAG TAT AAT AGT TAC CCT CC

  FM164406,IGKV1-16*02            --- --- --- --- --- --- --- --- --- --- --- --  °

° genomic DNA, but not known as being germline or rearranged


Created: 25/03/1997
Last updated: Wednesday, 29-Jun-2011 17:05:45 CEST
Author: Valérie Barbié
Contact: Marie-Paule Lefranc

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