3D representation: Mouse
(Mus musculus) two associated V-DOMAINs from D1.3Fv (PDB: 1dvf_A and 1dvf_B)
IMGT/3Dstructure-DB card: 1dvf
Colliers de Perles: IGH V-D-J-REGION
Colliers de Perles: IGK V-J-REGION
Side view (backbone model)
A V-DOMAIN corresponds to the V-J-REGION or V-D-J-REGION of the immunoglobulin and T cell receptor chains.
This figure shows the two associated V-DOMAINs isolated from an antibody and constituting what is called a "Fv" (for "fragment variable")
- CDR-IMGT regions are colored according to the IMGT color menu:
IGK V-J-REGION: CDR1-IMGT (blue), CDR2-IMGT (green), CDR3-IMGT (dark green)
IGH V-D-J-REGION: CDR1-IMGT (red), CDR2-IMGT (orange), CDR3-IMGT (purple).
- V-DOMAIN strands are colored according to the IMGT color menu for strand representation: A, B and C strands (orange), C' and C'' strands (green), D strand (yellow), E, F and G strands (blue).
- This image has been generated with the program RASMOL version 2.6 from the PDB file 1dvf, containing the atomic coordinates of the complex between Idiotope D1.3 -Antiidiotope E5.2. Both D1.3 (1dvf_A, 1dvf_B)and E5.2 (1dvf_C, 1dvf_D) are mouse antibodies (Mus musculus) IgG1, kappa. Only the D1.3 Fv is displayed here.
DOMAIN in IMGT Index
IMGT 2D and 3D representations (examples) in IMGT Repertoire.
Last updated: Monday, 20-Jan-2020 21:00:30 CET
Author: Marie-Paule Lefranc
Editor: Elodie Foulquier